Positions：Researcher
Phone：(+86)-731-84619763
Fax：(+86)-731-4612685
E-mail：nnkxf@isa.ac.cn
Professional Experience:
Assistant Professor (7/2006-10/2007) Institute of Subtropical Agriculture, Chinese Academy of Sciences
Associate Professor (10/2007-8/2012) Institute of Subtropical Agriculture, Chinese Academy of Sciences
Professor (9/2012-present) Institute of Subtropical Agriculture, Chinese Academy of Sciences
Business Address:
Key Laboratory of Agro-ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Yuanda Road (Second) #644, Changsha, Hunan 410125, China. Tel: 86-731-84619706 (O); Fax: 86-731-84612685. E-mail: nnkxf@isa.ac.cn.
Education:
B.A. 1996.9-2000.7 Henan Agricultural University (Veterinary Medicine)
M.S. 2000.9-2003.7 Nanjing Agricultural University (Clinical Veterinary Medicine)
Ph.D. 2003.9- Nanjing Agricultural University (Clinical Veterinary Medicine)
Post doctor 2007.9-2009.12 Nanchang University (Swine nutrition and dietary additive)
Visiting scholar 2005.7-2006.6 Key Laboratory of Animal Nutrition and Health, Institute of Subtropical Agriculture, Chinese Academy of Sciences (Swine nutrition and dietary additive)
Visiting scholar 2008.2-2009.2 Department of Animal Science, Texas A&M University (Nutritional biochemistry of amino acids)
Continuing Education:
Attended “Techniques for Writing and Presenting Scientific Papers Training Course” presented by Dr. Micheal Grossman, University of Illinois and successfully gained the Course Certificate.
Research Interests:
Swine amino acid nutrition, development and regulation of conceptus in Chinese local pig breeds, development and regulation of gut microorganism in pig, development of Chinese herbal feed additives.
As Principal Investigator (PI)
2008.10-2010.10 Program of Science and Technology of Hunan Province “Development and regulation of intestinal microecology in Ningxiang piglets” (2008NK3141).
2008.1-2010.12 Knowledge Innovation Program of Institute of Subtropical Agriculture, Chinese Academy of Sciences “Development and nutritional regulation of intestinal microecology in Guangxi mini-piglets” (ISACX-LYQY-QN-0703).
2009.1-2011.1 National spark program of China “Development of industrial production techniques with high-efficiency and low-volley in Huanjiang mini-pigs” (2007EA790004).
2010.1-2012.12 Project from National Natural Science Foundation of China “Mechanism of arginine nutrition regulating survival and growth of fetus during early trimester of pregnancy in gilt” (30901040).
2011.1-2012.12 Knowledge Innovation Program of the Chinese Academy of Sciences “Development of control technique of drug-resistance bacteria transmission in swine production” (KZCX2-EW-QN411).
As Collaborator：
2000.12-2003.7 Project from National Natural Science Foundation of China “Mechanism of immunologic enhancement of Chinese herbal ingredients and development of novel immunoenhancer” (30070566).
2003.12-2005.7 Project from National Natural Science Foundation of China “Mechanism of Chinese herbal medicament known as New Fertility-promoting Intrauterine Infusion Liquid in prevention and treatment of dam endometritis” (30371057).
2007.2-2009.10 Project from National Basic Research Program of China “Study on partition pattern of main nutrients in tissue and organ of pigs and its regulation mechanism” (2004CB117502).
2012.1-2014.12 Project from National Natural Science Foundation of China “Metabonomics study on arginine regulating intestinal mucosa development and impairment recovery in piglets” (31101729).
2012.1-2016.12 Project from National Basic Research Program of China “Regulation of nitrogen metabolism on growth and quality of muscle in pigs” (2012CB124704).
[1]XF Kong, YL Hu, R Rui, et al. Effects of Chinese herbal medicinal ingredients on peripheral lymphocyte proliferation and serum antibody titer after vaccination in Chicken. Int Immunopharmac, 2004, (4): 975-982.
[2]XF Kong, YL Hu, YL Yin, et al. Chinese herbal ingredients are effective immune stimulators for Chickens infected with the Newcastle disease virus. Poult Sci, 2006, 85(12): 2169- 2175.
[3]XF Kong, YL Yin, GY Wu, et al. Dietary supplementation with Acanthopanax senticosus extract modulates cellular and humoral immunities in weaned piglets. Asian-Aust J Anim Sci, 2007, 20(9): 1453-1461.
[4]XF Kong, GY Wu, YP Liao, et al. Dietary supplementation with Chinese herbal ultra-fine powder enhances cellular and humoral immunity in early-weaned piglets. Livest Sci, 2007, 108: 94-98.
[5]XF Kong, GY Wu, YP Liao, et al. Effects of Chinese herbal ultra-fine powder as a dietary additive on growth performance, serum metabolites and intestinal health in early-weaned piglets. Livest Sci, 2007, 108: 272-275.
[6]XF Kong, YL Yin, QH He, et al. Dietary supplementation with Chinese herbal powder enhances ileal digestibilities and serum concentrations of amino acids in young pigs. Amino Acids, 2009, 37: 573-582.
[7]XF Kong, FG Yin, QH He, et al. Acanthopanax senticosus extracts as a dietary additive enhances the apparent ileal digestibility of amino acids in weaned piglets. Livest Sci, 2009, 123(2-3):261-267.
[8]XF Kong, YZ Zhang, YL Yin, et al. Chinese Yam polysaccharide enhances growth performance and cellular immune response in weanling rats. J Sci Food & Agric, 2009, 89: 2039-2044.
[9]XF Kong, YZ Zhang, X Wu, et al. Fermentation characterization of the Chinese Yam polysaccharide and its effects on the gut microbiota of rats. Int J Microb, 2009, doi: 10.1155/ 2009/598152.
[10] XF Kong, GY Wu, YL Yin. Roles of phytochemicals in amino acid nutrition. Front Biosci, 2011, S3: 372-384.
[11] XF Kong, BE Tan, YL Yin, et al. Arginine stimulates the mTOR signaling pathway and protein synthesis in porcine trophectoderm cells. J Nutr Biochem, 2012, 23: 1178-1183.
[12] ZM Feng, JP Guo, XF Kong*, et al. Molecular cloning and expression profiling of G protein coupled receptor 120 in Landrace pig and different Chinese indigenous pig breeds. J Food Agric & Environ, 2012, 10: 809-814.
[13] ZM Feng, JP Guo, XF Kong*, et al. Which housekeeping gene can be well used in gene expression analysis in Chinese local pig breeds. J Food Agric & Environ, 2012, 10: 825-833.
[14] HS Yang, DZ Fu, H Shao, XF Kong*, et al. Impacts of birth weight on plasma, liver and skeletal muscle neutral amino acid profiles and intestinal amino acid transporters in suckling Huanjiang mini-piglets. Plos ONE, 2012, 7(12): e50921.
[15] ZM Feng, XL Zhou, H Shao, XF Kong*, et al. Genotyping of five Chinese local pig breeds focused on meat quality by using PCR-RFLP based on halothane and Mx1. J Food Agric & Environ, 2012, 10: 840-845.
[16] DZ Fu, HS Yang, XF Kong*, et al. Molecular cloning and expression profiling of excitatory amino acid carrier 1 in Huanjiang mini-piglets with different body weight. Mol Biol Rep, 2013, 40(4): 3341-3350.
[17] WC Wang, F Blachier, DZ Fu, J Pan, HS Yang, JP Guo, WY Chu, XF Kong*, et al. Ontogenic expression of the amino acid transporter b0,+ AT in suckling Huanjiang mini-piglets with different body weight. Br J Nutr, 2013, 110: 823-830.
[18] XF Kong, XL Zhou, GQ Lian, et al. Dietary supplementation with chitooligosaccharides alters gut microbiota and modifies intestinal luminal metabolites in weaned Huanjiang mini-piglets. Livest Sci, 2014, 160: 97-101.
[19] XF Kong, Wang XQ, Yin YL, et al. Putrescine stimulates the mTOR signaling pathway and protein synthesis in porcine trophectoderm cells. Biol Reprod, 2014, 91(5): 106, 1-10.
[20] XL Zhou, XF Kong*, GQ Lian, et al. Dietary supplementation with soybean oligosaccharides increases short-chain fatty acids but decreases protein-derived catabolites in the intestinal luminal content of weaned Huanjiang mini-piglets. Nutr Res, 2014, 34: 780-788.
[21] XF Kong#*, XL Zhou#, ZM Feng, et al. Dietary supplementation with monosodium L-glutamate modifies lipid composition and gene expression related to lipid metabolism in growing pigs fed a normal- or high-fat diet. Livest Sci, 2015, 247-252.
[22] YY Liu#, XF Kong#, GL Jiang, et al. Effects of dietary protein/energy ratio on growth performance, carcass trait, meat quality, and plasma metabolites in pigs of different genotypes. J Anim Sci & Biotechnol, 2015, 6: 36, 435-444.
[23] YY Liu, FN Li, XF Kong*, et al. Signaling pathways related to protein synthesis and amino acid concentration in pig skeletal muscles depend on the dietary protein level, genotype and developmental stages. PLoS ONE, 2015, 10(9): e0138277.
[24] YY Liu#, FN Li#, LY He, BE Tan, JP Deng, XF Kong*, et al. Dietary protein intake affects expression of genes for lipid metabolism in porcine skeletal muscle in a genotype-dependent manner. Br J Nutr, 2015, 113(7): 1069-1077.
[25] XF Kong*#, YJ Ji#, HW Li, et al. The colonic luminal bacteria community in Huanjiang mini-pigs fed diets with different nutrient levels from the first to third trimester of pregnancy. Sci Rep, 2016, 6: 37224.
[26] YY Liu, XF Kong*, FN Li, et al. Co?dependence of genotype and dietary protein intake to affect expression on amino acid/peptide transporters in porcine skeletal muscle. Amino Acids, 2016, 48: 75-90.
[27] YJ Ji, HN Liu, XF Kong*, et al. Use of insect powder as a source of dietary protein in early-weaned piglets. J Anim Sci, 2016, 94: 111-116.
[28] GL Jiang, YY Liu, AO Oso, FN Li, XF Kong*, et al. The differences of bacteria and bacterial metabolites in the colon between fatty and lean pigs. J Anim Sci, 2016, 94: 349-353.
[29] YJ Ji, XF Kong*, HW Li, et al. Effects of dietary nutrient level on microbial community composition and diversity in ileal contents of pregnant Huanjiang mini-pigs. PLOS One, 2017, 12(2): e0172086.
[30] CJ Hu, QY Jiang, T Zhang, YL Yin?, FN Li, JP Deng, GY Wu, XF Kong?. Dietary supplementation with arginine and glutamic acid modifies growth performance, carcass traits, and meat quality in growing-finishing pigs. J Anim Sci, 2017, 95: 2680-2689.
[31] CJ Hu, QY Jiang, T Zhang, YL Yin?, FN Li, JY Su, GY Wu, XF Kong?. Dietary supplementation with arginine and glutamic acid enhances key lipogenic gene expression in growing pigs. J Anim Sci, 2017, 95(12): 5507-5515.
[32] YJ Ji#, QP Guo#, YL Yin, F Blachier, XF Kong*. Dietary proline supplementation alters colonic luminal microbiota and bacterial metabolite composition between days 45 and 70 of pregnancy in Huanjiang mini-pigs. J Anim Sci & Biotechnol, 2018, 9: 18.
[33] Q Zhu, PF Xie, HW Li, C Ma, WH Zhang, YL Yin, XF Kong*. Fetal Huanjiang mini-pigs exhibit differences in nutrient composition according to body weight and gestational period. PLoS ONE, 2018, 13(7): e0199939.
[34] JY Su, Q Zhu, Y Zhao, L Han, YL Yin, F Blachier, ZB Wang, XF Kong*. Dietary supplementation with Chinese herbal residues or their fermented products modifies the colonic microbiota, bacterial metabolites, and expression of genes related to colon barrier function in weaned piglets. Front Microbiol, 2018, 9: 3181.
[35] CJ Hu, FN Li, YH Duan, XF Kong*, et al. Leucine alone or in combination with glutamic acid, but not with arginine, increases biceps femoris muscle and alters muscle AA transport and concentrations in fattening pigs. J Anim Physiol & Anim Nutr, 2019, 103(3): 791-800.
[36] H Li#, HW Li#, PF Xie, ZH Li, YL Yin, F Blachier, XF Kong*. Dietary supplementation with fermented Mao-tai lees beneficially affects gut microbiome structure and function in pigs. AMB Exp, 2019, 9: 26.
[37] YH Duan, Y Zhao, Q Zhu, QL Cai, HW Li, YL Yin, ZB Wang, XF Kong*. Dietary nutrient levels alter the metabolism of arginine family amino acids in the conceptus of Huanjiang mini-pigs. J Sci Food & Agric, 2019, 99(5): 2132-2139.
[38] WH Zhang, C Ma, PF Xie, Q Zhu, XD Wang, YL Yin, XF Kong*. Gut microbiota of newborn piglets with intrauterine growth restriction have lower diversity and different taxonomic abundances. J Appl Microbiol, 2019, 127: 354-369.
[39] YJ Ji#, H Li#, PF Xie, ZH Li, HW Li, YL Yin, F Blachier, XF Kong*. Stages of pregnancy and weaning influence the gut microbiota diversity and function in sows. J Appl Microbiol, 2019, 127: 867-879.
[40] CJ Hu, FN Li, YH Duan, YL Yin, XF Kong*. Dietary supplementation with leucine or in combination with arginine decreases body fat weight and alters gut microbiota composition in finishing pigs. Front Microbiol, 2019, 10: 1767.
[41] CJ Hu, FN Li, YH Duan, YL Yin, XF Kong*. Glutamic acid supplementation reduces body fat weight in finishing pigs when provided solely or in combination with arginine and it is associated with colonic propionate and butyrate concentrations. Food & Funct, 2019, 10: 4693-4704.
[42] CJ Hu, FN Li, YH Duan, T Zhang, HW Li, YL Yin, GY Wu, XF Kong*. Dietary supplementation with arginine and glutamic acid alters the expression of amino acid transporters in skeletal muscle of growing pigs. Amino Acids, 2019, 51: 1081-1092.
[43] J Yin, FN Li*, XF Kong*, et al. Dietary xylo-oligosaccharide improves intestinal functions in weaned piglets. Food & Funct, 2019, 10(5): 2701-2709.
[44] J Pan, J Yin, K Zhang, PF Xie, H Ding, XG Huang*, B Francois, XF Kong*. Dietary xylo-oligosaccharide supplementation alters gut microbial composition and activity in pigs according to age and dose. AMB Exp, 2019, 9: 134.
[45] JY Yang, BE Tan, QH He, YL Yin, GY Wu, XF Kong*. Dynamic changes in circulating levels of metabolites in the portal-drained viscera of finishing pigs receiving acute administration of L-arginine. J Anim Physiol & Anim Nutr, 2020, doi: 10.1111/ jpn.13350.
[46] Shao YR#, Zhou J#, Xiong X*, Zou LJ, Kong XF*, et al. Differences in gut microbial and serum biochemical indices between sows with different productive capacities during perinatal period. Front Microbiol, 2020, 10: 3047.
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