Faculty

Fengna LiPh.D, Professor

Positions：

Phone：13574168188

Fax：(+86)731-84612685

E-mail：lifengna@isa.ac.cn

Resume

Professional Experience:
Assistant Professor (7/2009-11/2011) Institute of Subtropical Agriculture,
Associate Professor (11/2011-present) Chinese Academy of Sciences

EDUCATION:
B.A. 1999.9-2003.7 Hunan Agricultural University (Animal Nutrition)
M.S. 2003.9-2006.7 Hunan Agricultural University (Animal Nutrition)
Ph.D. 2006.9-2009.6 China Agricultural University (Animal Nutrition)
RESEARCH INTEREST.
Animal Production; Animal Feed; Nutrition and Physiology of Amino Acids and
Protein; Growth and Development of Animals; Nutritional Biochemistry and Physiology; Immunonutrition

Direction

Current project

As Principal Investigator (PI)
2011.1-2013.12 Knowledge Innovation Program of Institute of Subtropical Agriculture, Chinese Academy of Sciences “N-6/n-3 polyunsaturated fatty acids ratio involved in regulating the energy metabolism and inflammation of pigs” (ISACX-LYQY-QN-1104).
2011.1-2013.12 Project from National Natural Science Foundation of China “The regulation and mechanism of myokine IL-15 on lipid deposition of porcine intramuscular adipocyte” (31001015).
2011.1-2013.12 Project from State Key Laboratory of Animal Nutrition “The pathway and mechanism of adipokine Chemerin on proliferation and differentiation of myoblast” (2004DA125184F1113).

Community service

Achievements

Article

1.LY Zhang, QP Guo, YH Duan, WL Wang, YH Yang, YJ Yin, SM Gong, MM Han, Li FN*, YL Yin. Potential nutritional healthy-aging strategy: enhanced protein metabolism by balancing branched-chain amino acids in a finishing pig model. Food and Function. 2022, 13(11): 6217-6232.

2.Zhou XH, Liu YH, Xiong X, Chen JQ, Tang WJ, He LQ*, Zhang ZG, Yin YL*, Li FN*. Intestinal accumulation of microbiota-produced succinate caused by loss of microRNAs leads to diarrhea in weanling piglets. Gut Microbes. 2022, 14(1): 2091369.

3.Zhang LY, Li FN*, Guo QP, Duan YH, Wang WL, Yang YH, Yin YJ, Gong SM, Han MM, Yin YL. Balanced branched-chain amino acids modulate meat quality by adjusting muscle fiber type conversion and intramuscular fat deposition in finishing pigs. Journal of the Science of Food and Agriculture, 2022, 102(9): 3796-3807.

4.He LQ, Zhou XH, Liu YH, Zhou LM, Li FN*. Fecal miR-142a-3p from dextran sulfate sodium challenge recovered mice prevents colitis by promoting the growth. Molecular Therapy, 2022, 30(1): 388-399.

5.Wang WL, Li FN*, Duan YH, Guo QP, Zhang LY, Yang YH, Yin YL, Han MM, Gong SM, Li JZ, He SP, Yin YL. Effects of Dietary Chlorogenic Acid Supplementation Derived from Lonicera macranthoides Hand-Mazz on Growth Performance, Free Amino Acid Profile, and Muscle Protein Synthesis in a Finishing Pig Model. Oxidative Medicine and Cellular Longevity, 2022: 6316611.

6.Duan YH, Song B, Zheng CB, Zhong YZ, Guo QP, Zheng J, Yin YL, Li JJ, Li FN*. Dietary Beta-Hydroxy Beta-Methyl Butyrate Supplementation Alleviates Liver Injury in Lipopolysaccharide-Challenged Piglets. Oxidative Medicine and Cellular Longevity, 2021: 5546843.

7.Zhou XH, Liu YH, Zhang LY, Kong XF, Li FN*. Serine-to-glycine ratios in low-protein diets regulate intramuscular fat by affecting lipid metabolism and myofiber type transition in the skeletal muscle of growing-finishing pigs. Animal Nutrition, 2021, 7:384-392.

8.Zhong YZ, Yan ZM, Song B, Zheng CB, Duan YH, Kong XF, Deng J, Li FN*. Dietary supplementation with betaine or glycine improves the carcass trait, meat quality and lipid metabolism of finishing mini-pigs. Animal Nutrition, 2021, 7:376-383.

9.Liu YY, Li Y, Xiao Y, Peng YL, He JH, Chen C, Xiao DF, Yin YL, Li FN*. Mulberry leaf powder regulates antioxidative capacity and lipid metabolism in finishing pigs. Animal Nutrition, 2021, 7:421-429.

10.Zhang LY, Li FN*, Guo QP, Duan YH, Wang WL, Yang YH, Yin YJ, Gong SM, Han MM, Yin YL. Different proportions of branched-chain amino acids modulate lipid metabolism in a finishing pig model. Journal of Agricultural and Food Chemistry, 2021, 69:7037-7048.

11.Wen CY, Guo QP, Wang WL, Duan YH, Zhang LY, Li JZ, He SP, Chen W, Li FN*. Taurine Alleviates Intestinal Injury by Mediating Tight Junction Barriers in Diquat-Challenged Piglet Models. Frontiers in Physiology, 2020, 11: p449.

12.Zhang LY, Duan YH, Guo QP, Wang WL, Li FN*. A selectively suppressing amino acid transporter: Sodium-coupled neutral amino acid transporter 2 inhibits cell growth and mammalian target of rapamycin complex 1 pathway in skeletal muscle cells. Animal Nutrition, 2020, 6:513-520.

13.Yan ZM, Zhong YZ, Duan YH, Chen QH, Li FN*. Antioxidant mechanism of tea polyphenols and its impact on health benefits. Animal Nutrition, 2020, 6:115-123.

14.Zhang LY, Li FN*, Guo QP, Duan YH, Wang WL, Zhong YZ, Yang YH, Yin YL. Leucine Supplementation: A Novel Strategy for Modulating Lipid Metabolism and Energy Homeostasis. Nutrients, 2020, 12:1299.

15.Wen CY, Li FN*, Guo QP, Zhang LY, Duan YH, Wang WL, Li JZ, He SP, Chen W, Yin YL. Protective effects of taurine against muscle damage induced by diquat in 35 days weaned piglets. Journal of Animal Science and Biotechnology, 2020, 11:56.

16.Guo QP, Li FN*, Wen CY, Zhang LY, Duan YH, Wang WL, Huang RL, Yin YL. The changes in growth performance and lipid metabolism of pigs with yellow fat induced by high dietary fish oil. Canadian Journal of Animal Science, 2020, 100: 154-164.

17.Guo QP, Li FN*, Duan YH, Wen CY, Wang WL, Zhang LY, Huang RL, Yin YL. Oxidative stress, nutritional antioxidants and beyond. SCIENCE CHINA-Life Sciences. 2020, 63(6): 866-874.

18.Duan YH, Li FN*, Song B, Zheng CB, Zhong YZ, Xu Kang, Kong XF, Yin YL, Wang WC, Shu G. β-hydroxy-β-methyl butyrate, but not α-ketoisocaproate and excess leucine, stimulates skeletal muscle protein metabolism in growing pigs fed lowprotein diets. Journal of Functional Foods. 2019, 52: 34-42.

19.Wen CY, Li FN*, Duan YH, Guo QP, Wang WL, Zhang LY, Li JZ, He SP, Chen W, Yin YL. Dietary taurine regulates free amino acid profiles and taurine metabolism in piglets with diquat-induced oxidative stress. Journal of Functional Foods. 2019, 62: 103569.

20.Wen CY, Li FN*, Zhang LY, Duan YH, Guo QP, Wang WL, He SP, Li JZ, Yin YL. Taurine is involved in energy metabolism in muscles, adipose tissue, and the liver. Molecular Nutrition and Food Research. 2019, 63: 1800536.

21.Liu YY#, Li YH#, Peng YL, He JH, Xiao DF, Chen C, Li FN*, Huang RL, Yin YL. Dietary mulberry leaf powder affects growth performance, carcass traits and meat quality in finishing pigs. Journal of Animal Physiology and Animal Nutrition. 2019, 103:1934–1945.

22.Duan YH, Li FN*, Guo QP, Wang WL, Zhang LY, Wen CY, and Yin YL. Branched-chain amino acid ratios modulate lipid metabolism in adipose tissues of growing pigs. Journal of Functional Foods. 2018, 40: 614-624.

23.Duan YH#, Zhang LY#, Li FN*, Guo QP, Long CM, Yin YL, Kong XF, Peng MJ, Wang WC. Beta-Hydroxy-beta-methylbutyrate modulates lipid metabolism in adipose tissues of growing pigs. Food & Function. 2018, 9: 4836-4846.

24.Li YH, Li FN*, Duan YH, Guo QP, Wen CY, Wang WL, Huang XG, Yin YL. Low-protein diet improves meat quality of growing and finishing pigs through changing lipid metabolism, fiber characteristics, and free amino acid profile of the muscle. Journal of Animal Science. 2018, 96(8): 3221-3232.

25.Li YH#, Liu YY#, Li FN*, Lin Q, Dai QZ, Sun JB, Huang XG, Chen XA, Yin YL. Effects of dietary ramie powder at various levels on carcass traits and meat quality in finishing pigs. Meat Science. 2018, 143:52-59.

26.Li FN, Li YH, Duan YH, Hu CA, Tang YL, Yin YL. Myokines and adipokines: Involvement in the crosstalk between skeletal muscle and adipose tissue. Cytokine & Growth Factors Review. 2017, 33:73-82.

27.Li YH, Li FN*, Duan YH, Guo QP, Wang WL, Wen CY, Huang XG, Yin YL. The protein and energy metabolic response of skeletal muscle to the low-protein diets in growing pigs. Journal of Agricultural and Food Chemistry. 2017, 65(13): 8544-8551.

28.Duan YH, Li FN*, Guo QP, Wang WL, Zhang LY, Wen CY, and Yin YL. Branched-chain amino acid ratios modulate lipid metabolism in adipose tissues of growing pigs. Journal of Functional Foods. 2018, 40: 614-624.

29.Duan YH, Li FN*, Tan BE, Yao K, Yin YL. Metabolic control of myofibers: promising therapeutic target for obesity and type 2 diabetes. Obesity reviews. 2017, 18(6):647-659.

30.Duan YH, Li FN*, Wang WL, Guo QP, Wen CY, Li YH, Yin YL. Interleukin-15 in obesity and metabolic dysfunction: current understanding and future perspectives. Obesity reviews. 2017, 18 (10):1147-1158.

31.Li YH, Wei HK, Li FN*, Duan YH, Guo QP, Yin YL. Effects of Low-Protein Diets Supplemented with Branched-Chain Amino Acid on Lipid Metabolism in White Adipose Tissue of Piglets. Journal of Agricultural and Food Chemistry. 2017, 65(13):2839-2848.

32. Duan YH, Zeng LM, Li FN*, Wang WL, Li YH, Guo QP, Ji YJ, Tan BE, Yin YL. Effect of branched-chain amino acid ratio on the proliferation, differentiation and the expression levels of key regulators involved in protein metabolism of myocytes. Nutrition. 2017, 36:8-16.

33.Li YH, Li FN*, Wu L, Liu YY, Wei HK, Li TJ, Tan BE, Kong XF, Wu F, Duan YH, Oladele OA, Yin YL. Reduced dietary protein level influences the free amino acid and gene expression profiles of selected amino acid transceptors in skeletal muscle of growing pigs. Journal of Animal Physiology and Animal Nutrition (Berl). 2017, 101:96-104.